From forensic to medical
In the 1970s, Mr Brenneisen took his first steps as a cannabis scientist, but in the forensic sphere. On the instructions of the Swiss Drogenpolizei he was at the cradle of a reliable method for determining the THC content of cannabis, and then moved to the Research Institute of Pharmaceutical Sciences in Oxford Mississippi, where together with Professor Mahmoud ElSohly he worked on the chemical fingerprint (terpenoids profiling) of the cannabis plant and its active components (cannabinoids). This knowledge brought Mr Brenneisen to the laboratory of the Drug Enforcement Administration (DEA) in McLean, Virginia around the middle of the 1980s. A beautifully framed certificate on the wall in Mr Brenneisen’s office in Bern serves as a daily reminder of that period. In the end, a pilot study with muscle-spasm patients brought the Swiss cannabis specialist back to his country of birth.
“That was a definite move from forensic to medical science”, said Mr Brenneisen. “That study, where initially two patients were treated with THC, proved to be a milestone in cannabis research. The study was scaled up to several patients and actually opened the door to clinical studies of cannabis in Switzerland. Perhaps even in the rest of the world, because after that many trials were started up in the area of neurological disorders, such as Amyotrophic Lateral Sclerosis (ALS) and pain.”